![]() ![]() Loboob offered a dose-dependent protective effect on several sperm parameters in rats with busulfan-induced subfertility. ![]() ![]() It did not improve normal morphology sperm or decrease immotile sperm counts. Loboob at a dosage of 140mg/kg improved sperm viability. All dosages of Loboob were effective to enhance the motility of slow spermatozoa, while only in the rats given 70 and 140 mg/kg of Loboob saw improvements in progressively motile sperm percentages (0.024 and 0.01, respectively). Finally, the sperm parameters and weights of the rats were compared using the Kolmogorov-Smirnov, non-parametric Kruskal-Wallis, and Dunn-Bonferroni tests.Īll sperm parameters and weights were significantly decreased among rats receiving Busulfan. Rats in Treatment Group 1 received 10mg/kg Busulfan and rats in Treatment Groups 2, 3, and 4 received 35,70 and 140 mg/kg Loboob respectively in addition to 10mg/kg Busulfan. The control group received no medication. The aim of this experimental study was to determine the effect of Loboob on sperm parameters.ĥ5 healthy rats were selected, weighted and divided into five groups consisting of 11 rats each. Male infertility secondary to exposure to gonadotoxic agents during reproductive age is a concerning issue. ![]()
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